Nanofluidic platform for on-chip real-time binding kinetic assays

Description

Dynamics of protein-protein interactions is central to understand the cell machinery and to develop new drugs. While SPR affinity- based sensors are now routinely used, they suffer from a lack of sensitivity when analyzing small molecules interactions or high kinetic rate reactions. Furthermore, the requirement of highly skilled personal and expensive equipment, hampers their wide diffusion.
Our solution : nanofluidic platform for kinetic assays.

Applications

Characterization of biomolecular interaction in:
  • Fundamental life-science studies
  • Drug screening
  • ¬†Immunogenicity test
  • Companion test