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Life Tech
Therapeutics
Formulating medications to improve their solubility
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New encapsulation method improving the performance of a medication
Validated with two poorly soluble medications in the public domain:
- Taxol, a very poorly soluble, highly unstable cancer medication (requires reconstitution immediately before treatment), causing numerous effects that can stop treatment
- Rapamycin, immunosuppressant for kidney transplants, currently being repositioned as a cancer medication, also very poorly soluble
Competitive advantages
- Simple, inexpensive and versatile formulation (POC on 2 different medications)
- Non-toxic biosourced compound
- Large volume of medications on board
- Improved medication solubility: easier administration and lower doses administered and therefore fewer side effects
Applications
Medication formulation
Intellectual property
Expertise
Development stage
Experimental proof of concept
Laboratory
SOFTMAT Université Paul Sabatier
Technical specifications
- Encapsulation protocol: Two simple steps, at room temperature and pressure, using a biosourced compound
- Results showing higher final medication concentrations with the biosourced compound
- Significant decrease in IC50 with encapsulation by the biosourced compound